Published: 2026-10-17

Review Articles

Hypertension Management in Low-Resource African Settings: Current Approaches and Key Challenges

Gift Obele Philip

1255 - 1262

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386 100
DOI: https://doi.org/10.71637/tnhj.v26i3.1448

A Two-Year Clinical Audit of Caesarean Section Rates Using the Robson Ten-Group Classification System at a Busy Health Facility in Niger Delta Region, Nigeria

Olumuyiwa Ogunlaja, Bunmi Adetula, Osborne Osuegbu, Ugochi Anyanwu, Chidozie Onyedinma, Divine Tuboteme, Francis Ebarentonbofa, Idowu Ogunlaja, Benjamin Osaro, Chika Duru, Aloni Alali, Akinwumi Fajola, Goodness Danson

1567 – 1575

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280 77
DOI: https://doi.org/10.71637/tnhj.v26i3.1511

Telehealth in Underserved Populations: A Review of Policy, Regulation, Ethics, Future innovations, and Effectiveness of Telemedicine in Bridging Healthcare Gaps in Rural and Low-Resource Settings

Oluyemisi Okwudishu, Victor Chimezie Okebalama, Eke Desmond Onyebuchukwu, Peter Oluwasegun Odunuyi, Odutola Odugbemi, Opadotun Olauwafemi Ayotunji, Zoe Ndukwe, Cyprian Okoronkwo, Chidinma Halliday, Chigozie Ugochukwu, John oluwajuwon olawoye, Cyril Akwuruoha, David Akwuruoha, Oluwatobi Aremu, Omoniyi Olumobi Akinnifesi

1608 - 1624

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207 108
DOI: https://doi.org/10.71637/tnhj.v26i3.1522

A Structured Review of TNF-α–NF-κB Axis in Arthritis: Molecular Mechanisms, Natural Anti-Inflammatory Agents, and Advanced Therapeutic and Predictive Strategies

Veshalini Kasiraja, Agustika Antoni, Zaidatul Akmal Othman, Noor Azlina Abu Bakar, Noor Azuin Suliman

1625 - 1639

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204 101
DOI: https://doi.org/10.71637/tnhj.v26i3.1527

Scoping Review of Implementation Strategies for Reaching Zero-Dose and Under-Immunized Children in Low- and Middle-Income Countries

Chibuike Innocent Agu, Oluchukwu Ifeyinwa Ezechukwu, Chinyere Ojiugo Mbachu

1702 - 1719

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200 64
DOI: https://doi.org/10.71637/tnhj.v26i3.1607

Mitigation Strategies for Nitrosamine Drug Substance Related Impurities: A Practical Framework for the Pharmaceutical Industry

Mahesh Vyas, Anil Pethe, Umesh Kale

1544 - 1552

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143 68
DOI: https://doi.org/10.71637/tnhj.v26i3.1504

Original Articles

Relationship between Stress, Socio-Demographic and Clinical Characteristics of Mothers and Preterm Infants in Neonatal Intensive Care Units

Abdul Mahdi A. Hasan, Mays Abbas Mohammed

1337 – 1346

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168 66
DOI: https://doi.org/10.71637/tnhj.v26i3.1460

Health System Responsiveness: The Perception of Private University Health Center by Nigerian Undergraduates 

Oyelola Eyinade Adeoye, Caleb Aderemi Adegbenro, Olumide Thomas Adeleke, Titilope Adetoun Bamikefa, Evans Chukwunenye Oliseh, Olajide Oluwasayo Oladunsi, Watrahyel James Mshelia, Dairo Iremide Mathew, Ebunoluwa Oyedayo Odejinmi

1681 – 1687

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162 68
DOI: https://doi.org/10.71637/tnhj.v26i3.1551

The Nexus between COVID-19 Shocks and Foreign Direct Investment in Nigeria

Charles Osondu Manasseh, Chine Sp Logan, Kenechukwu Kenneth Ede, Chiamaka Lucy Okeke, Afamefuna Joseph Nduka, Edith Nkiru Mazeli, Daniel Izuchukwu Chude, Nkiru Patricia Chude, Emeka Ejim

1111 – 1120

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84 63

QbD Based Method Development and Validation of Ursolic Acid from Rosmarinus officinalis by HPTLC Method

Rajashree Chavan, Vaishnavi Shinde, Prem Kale, Gitanjali Barade, Ganesh Nigade

1478 – 1491

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103 81
DOI: https://doi.org/10.71637/tnhj.v26i3.1496

High Awareness, Poor Utilization: A Cross-Sectional Study of Timing and Adequacy of Antenatal Care among Pregnant Women Attending Primary Health Centres in Yenagoa, Nigeria

Margaret Ebinabo Adigio, Peter Chukwudi Nwakile, Ruth Ebiegberi Obidake, Eneyi Edith Kpokiri

1282 – 1292

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255 72
DOI: https://doi.org/10.71637/tnhj.v26i3.1454

Family Management Styles Among Families of Children with Thalassemia

Dunya Fahem Shakir, Mohammed Talib Abed

1409 - 1415

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102 61
DOI: https://doi.org/10.71637/tnhj.v26i3.1481

Interplay Between Cardiac Injury Markers, Renal Function, and Lipid Profile in Hypertension: Evidence from a Case–Control Study

Chigaemezu Remmy-Martin Akubuo, Uche Melford Elendu, Chinedu Barry Iheukwumere, Chinwe Patrick Ugwuezumba, Nzubechukwu Eustacemary Nwosu, Feziechi Benigna Egwurugwu, Odichimma Paschaline Egwurugwu

1215 – 1226

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113 78
DOI: https://doi.org/10.71637/tnhj.v26i3.1440

Demographic Characteristics and Surgical Indications of Patients Undergoing Spine Surgery in a Nigerian Private Neurosurgical Practice: A Retrospective Review

Elijah Ali Usiholo, George Aighobahi Akpede, Hanson Osazuwa Idehen

1553 – 1559

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223 68
DOI: https://doi.org/10.71637/tnhj.v26i3.1505

Antibacterial Activity of Curcuma longa Linn. (Turmeric) Extracts on Selected Ocular Bacterial Isolates

Young Christian Azuamah, Udodiri Precious Uche, Wesley Braide

1347 – 1358

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82 48
DOI: https://doi.org/10.71637/tnhj.v26i3.1461

Pharmaceutical Cocrystals of Eplerenone Formulation and Characterization

Zainab M. Salih, Sakar Dilshad Asaad, Mohammed Majeed Hachem, Ahmed Mohamed kmkm, Rafif Raad, Ishraq Kadhim Abbas, Reyam sadiq, Ali Abass, Basma M. Hadi

1688 - 1701

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41 47
DOI: https://doi.org/10.71637/tnhj.v26i3.1552

Predictors of Awareness of Pain Management Options During Labour Among Pregnant Women Attending Antenatal Care Clinic at Federal Teaching Hospital, Birnin Kebbi: A Cross-sectional Study

Saidu Ibrahim, Abdulfattah Isa, Benedict Ikechukwu Okeke, Ayotunde Sherif Azees, Mustapha Saleem Ayodeji, Makinde Adebayo Adeniyi, Anas Ibrahim Yakubu, Hudu Garba Illo

1121 – 1131

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100 46
DOI: https://doi.org/10.71637/tnhj.v26i3.1298

RP-HPLC Method Development and Validation of C-Phycocyanin Using Marketed Formulation

Amol Kale, Chetan Natu, Divya Dhoke, Saurabh Bhosale, Ganesh Nigade, Smita Pawar

1492 – 1499

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111 71
DOI: https://doi.org/10.71637/tnhj.v26i3.1498

The Lived Experience of Adolescents with Lower Prosthetic Limb: A Phenomenological Study

Aqeel Saad Nayef, Zaid Waheed Ajil

1293 – 1301

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128 57
DOI: https://doi.org/10.71637/tnhj.v26i3.1455

Prevalence, Associated Factors and Management Outcomes of Prelabor Rupture of Membranes: A 10-Year Hospital-Based Retrospective Study

Oluwasomidoyin Olukemi Bello, Esther Oluwatoyin Famutimi, Olaolu Olayinka Oni

1416 - 1425

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111 54
DOI: https://doi.org/10.71637/tnhj.v26i3.1482

Prevalence and Impact of Dysmenorrhea among Female Students of EKSUTH College of Nursing Sciences

Gbenga Damilola Akinlua, Oluwole Dominic Olaogun, Toluwalase Ebenezer Ige, Olabisi Olayinka Awe, Kehinde Peter Animasahun

1227 – 1240

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217 63
DOI: https://doi.org/10.71637/tnhj.v26i3.1445

Trial of Labour After Caesarean Section (TOLAC), Pattern, Outcome and Contemporary Predictors in A Tertiary-Level Obstetric Population in Southwest Nigeria: A Retrospective Descriptive Analysis

Adebayo Duyile Adekunle, Oluniyi Ebenezer Oyedeji, Wakeel Okanlawon Muritala, Matthew Olusegun Fijabiyi, Muibat Adesola Adeniran, Oluwakemi Damilola Akindele, Yetunde Omolola Oyedeji, Adetunmise Oluseyi Olajide, Tola Yinka Bakare, Olufemi Opeyemi Aworinde, Adewale Samson Adeyemi, Adetunji Oladeni Adeniji

1560 – 1566

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95 75
DOI: https://doi.org/10.71637/tnhj.v26i3.1507

Age and Gender Differences in D-dimer, NGAL, and CD4 Levels Among HIV-Infected and Non-Infected Adults: A Case–Control Study

Ikechukwu Vincent Obi, Collins Uchechukwu Obi, Alfred Friday Ehighe, Chisom Divinefavour Onuora, Chinedu David Morah, Bernice Amala Ogolo, Nkiruka Chikaodili Egenti

1359 – 1367

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201 52
DOI: https://doi.org/10.71637/tnhj.v26i3.1465

Impact of a Structured Training Program on Nurses’ Knowledge and Self-Reported Skills in Suicide Assessment and Prevention: A Pilot Pretest–Posttest Study

Shafeah Makdour Aljedaani, Mona Ahmed El-Bilsha

1132 – 1147

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132 53
DOI: https://doi.org/10.71637/tnhj.v26i3.1312

Chest Expansion in Acute Stroke Survivors Admitted to the Stroke Ward of a Tertiary Health Institution: An Exploratory Cross-Sectional Study

Chigozie Okwudili Obaseki, SaintJob Osanimaga Isibor

1500 – 1509

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81 54
DOI: https://doi.org/10.71637/tnhj.v26i3.1500

Relationship Between Stress and Coping Strategies among Mothers of Hospitalized Preterm Infants in Neonatal Intensive Care Units

Abdul Mahdi A. Hasan, Mays Abbas Mohammed

1302 – 1309

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134 44
DOI: https://doi.org/10.71637/tnhj.v26i3.1456

Impact of Phthalates from Culture Materials on Histo-architecture of the Kidney, Liver and Muscle of Clarias gariepinus 

Kingsley Anene Ugwaka, Levi Ekene Okoye, Paul Abuchi Nwafor, Uzoamaka Francisca Muotolo, Lawretta Ngozi Azodo, Francisca Chinwendu Izukanne-Ezeoke, Margaret Ngozi Okeke, Jacinta Nwakaego Omumuabuike, Nneamaka Mariah Ilodigwe

1640 – 1652

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74 87
DOI: https://doi.org/10.71637/tnhj.v26i3.1533

Sociodemographic And Clinical Determinants of Health-Related Quality of Life of Patients with Type II Diabetes Mellitus: A Cross-Sectional Study

Cindy Goda Samuel-Udofia, Aihanuwa Eregie, Stephen Oluwakayode Aje, Kenneth Analechi Madume, Taofeek Oluwole Awotidebe, Olufunmilola Kehinde Akinniranye, Niyi David Akintayo, Cindy G. Samuel-Udofia, Onyeso Ogochukwu Kelechi, Francis Oluwatosin Kolawole, Bunmi Prosper Ehigie, Kayode I. Oke

1066- 1075

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183 48
DOI: https://doi.org/10.71637/tnhj.v26i3.1136

Depression among Undergraduates at the University of Calabar, Nigeria: Prevalence, Socio-Demographic Correlates, and Coping Strategies

Fidelis Takim Otu, Favour Ibe Okoi, Blessing Ejangobasi Agara, Samuel Emmanuel Dickson, Emilia Okon Andong

1426 – 1436

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111 52
DOI: https://doi.org/10.71637/tnhj.v26i3.1486

Economic Burden of Foodborne Illnesses among Farm Households in Ogun State, Nigeria

Chioma P. Adekunle, Tolulope O. Oyekale, Solomon O. Oladeji, Esther T. Tolorunloju, Oyeronke A. Adekola, Abayomi Olorunfemi

1241 - 1254.

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66 52
DOI: https://doi.org/10.71637/tnhj.v26i3.1446

Urban–Rural Differences in Preventive Medical Screening Uptake and Associated Factors among Adults in Nigeria: A Comparative Cross-Sectional Study

Elias C Aniwada, Chika N Onwasigwe

1368 – 1379

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118 48
DOI: https://doi.org/10.71637/tnhj.v26i3.1473

Occupational Differences in Plasma Lipid Profile and Lipid Peroxidation among Automobile Mechanics and Non-Exposed Adults in Southwestern Nigeria

Samuel Oluwasegun Ogundayomi, Adeseye Muyiwa Arogunjo, Ganiyu Oyebola Adeosun

1720 – 1733

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137 61
DOI: https://doi.org/10.71637/tnhj.v26i3.1622

Prophylactic Potentials of Allicumin Against Newcastle Disease Virus in Broiler Chicks

Harmony Iheukwumere Ikechukwu, Patricia Amaka Egbe, Ifeoma Perpetua Oragwu, Julius Nnamdi Ndive, Henry Chimamkpa Nnadozie, Bright Chukwuebuka Unaeze, Magret N. Okeke, Ifeoma Adaora Chima Mbachu, Chidiogo Marigold Iheukwumere, Kingsley Anane Ugwaka

1148 – 1164

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85 49
DOI: https://doi.org/10.71637/tnhj.v26i3.1355

Facilitators and Barriers to Effective Implementation of Integrated Disease Surveillance and Response Among Health Care Professionals in Tertiary Hospitals in Lagos State, Nigeria – A Cross-Sectional Survey

Peter John Okoma, Olubola Olaoluwa, Jane Chinazom Onwuekwe, Samuel Gbolagunte Olaniyan, Aliyu Muhammad Maigoro, Oluwole Olutomola Olutunde

1510 - 1521

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224 46
DOI: https://doi.org/10.71637/tnhj.v26i3.1501

Comparison of Home Food Hygiene Practices Between Mothers of Healthy-Weight Children and Mothers of Underweight Children

Yahaya Jafaru, Maryam Kabiru Haruna, Aisha Abdullahi Magaji

1310 – 1319

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82 49
DOI: https://doi.org/10.71637/tnhj.v26i3.1457

Relationship between Nutritional Status and Comorbidity Burden among Nursing Home Residents in the Middle Euphrates Region, Iraq: A Cross-Sectional Study

Ali Majid Hassan, Ali Jabbar Eidan, Murtadha Kanim Adea Aljebory

1653 – 1663

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103 48
DOI: https://doi.org/10.71637/tnhj.v26i3.1541

Evaluation of the Legal Protection of Online Health Service Platforms: A Cross-sectional Study in Indonesia

Suyanto Suyanto, Siti Nur Qomariah, Eileen Savage

1076 – 1086

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166 45
DOI: https://doi.org/10.71637/tnhj.v26i3.1156

Effects of Aqueous Moringa oleifera Seed Extract on Glycaemic Status, Haematological Parameters, Pancreatic Histology, and Insulin Expression in Streptozotocin-Induced Diabetic Wistar Rats

Leonard Obidimma Umunnakwe, Ifeyinwa Maryann Okafor, Esther Effiom Eyo, Anietie Michael Archibong, Grace Chimamanda Abang

1437 – 1450

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106 66
DOI: https://doi.org/10.71637/tnhj.v26i3.1489

Knowledge of Diet-Related Chronic Diseases and Dietary Practices among Adolescents in Akpabuyo Local Government Area, Cross River State, Nigeria

Josephine Eneji Egbung, Simon Alain Inah, Effanga Bassey Adam, Francis Ajor Ojeka, Amanda Erim Ogar, Clinton Daniel Madugu, Sylvia Ini Etim

1576 – 1588

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79 44
DOI: https://doi.org/10.71637/tnhj.v26i3.1512

Bioactivity-Guided Phytochemical Investigation, Isolation of Marker Compounds, and Development of an Ayurvedic Formulation (Jalparni Arishta) from Eichhornia crassipes with Evaluation of Hepatoprotective and Nephroprotective Potential Against Lead Acetate–Induced Toxicity in Wistar Rats

Shital Kalekar, Devang Pandya

1380 – 1391

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63 44
DOI: https://doi.org/10.71637/tnhj.v26i3.1474

Menstrual Health Literacy and Menstrual Hygiene Management: A School-based Cross-sectional Survey among Secondary School Girls in Ebonyi State, Nigeria

Benedicta Onyinyechi Nte, Ignatius Obilor Nwimo, Rita Ngozika Ojide, Deborah Nnebuife Alegu, Nwamaka Agbe Elom, Christian Ikechukwu Ogah, Walter Ogar, Dom Enamhi

1165 – 1175

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211 58
DOI: https://doi.org/10.71637/tnhj.v26i3.1373

Stability Indicating Method Development and Validation of Dapsone Using RP-HPLC Technique

Mahesh Khatal, Manish Kumar

1522 – 1534

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67 44
DOI: https://doi.org/10.71637/tnhj.v26i3.1502

Genetic Variation of BCL11A in Beta Thalassemia Patients Infected with Human Parvovirus B19 and Human Herpesvirus-6

Esraa Abdulhaleem, Shakir Hammad Mohammed Al-Alwany, Ali Hmood Al-Saadi

1320 – 1328

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154 56
DOI: https://doi.org/10.71637/tnhj.v26i3.1458

Prevalence and Determinants of Psychoactive Substance Use among Secondary School Students in Abuja Municipal Area Council, Federal Capital Territory, Nigeria: A Cross-Sectional Study

Charity Kenechukwu Maduabuchi, Idris Muhammad Yakubu, Magayaki Gideon Paul, Anuoluwa Magareth Lawrence, Ummu'aiman Muhammad Makwashe, Luka Allen Kuyet, Muhammad-Hadi Folarin Oyerinde

1664 – 1673

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381 106
DOI: https://doi.org/10.71637/tnhj.v26i3.1545

Perceived Relevance of Nursing Process to Quality of Care Among Nurses in Selected Hospitals in Ibadan, Oyo State

Iyanuoluwa Oreofe OJO, Fehintola Aanu Olawunmi, Olufemi Oyebanji Oyediran, Prisca Olabisi Adejumo

1087 – 1098

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140 47
DOI: https://doi.org/10.71637/tnhj.v26i3.1182

Development and Characterization of a Polyherbal Phytosomal Formulation for Enhancement of Innate Immune Responses

Rishikesh Jagzap, Nitin Sutar

1451 – 1470

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71 60
DOI: https://doi.org/10.71637/tnhj.v26i3.1493

Understanding Hemodialysis Patients' Perceptions Towards Barriers to Physical Exercise: A Mixed-Methods Design

Saja Kareem Jassim, Serwan Jafar Bakey

1263 – 1274

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84 53
DOI: https://doi.org/10.71637/tnhj.v26i3.1451

Stability-Indicating RP-HPLC Determination of Rivaroxaban: Method Development, Validation, and Forced Degradation Study

Priyanka Vijendra Bagade, Nilesh Shrikant Kulkarni, Shashikant Nivrutti Dhole, Pravin Digambar Chaudhari, Ujwala Shivaji Desai

1589 – 1598

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84 67
DOI: https://doi.org/10.71637/tnhj.v26i3.1516

Formulation, Characterization, and Antioxidant Potential of a Novel Herbal Emulgel Containing Coccinia grandis and Curcuma longa Extracts

Swati Babaso Udugade, Sujata Abhay Jadhav, Vishwajeet Sampatrao Ghorpade

1392 – 1402

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74 49
DOI: https://doi.org/10.71637/tnhj.v26i3.1476

Patients’ Rights Awareness, Health-Seeking Behaviour, and Perceived Barriers to Rights Protection among Healthcare Users in Selected Facilities in Rivers State, Nigeria: A Convergent Mixed-Methods Study

Edward Ukwubile Egwuaba, Blessing Sunday Adeyi, Anastasia Ezinwanne Nwaobi, Benjamin Chike Okosa, Ugochukwu Ikenna Ibe, Anselm Uchechukwu Abonyi, John Arinze Eze, Ann Chinwe Akpunonu, Blessing Chidinma Nwakoby, Patricia Chinwe Iloka, Enright Que Okolie, Stella Chidimma Nwakoby, Monica Nkechi Ibeneme

1176 – 1195

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216 43
DOI: https://doi.org/10.71637/tnhj.v26i3.1433

A Computational Approach for Deriving Acceptable Intake (AI) of Nitrosamine Drug Substance Related Impurities (NDSRIs): A Read-Across and QSAR Based Framework

Mahesh Vyas, Anil Pethe, Umesh Kale

1535 – 1543

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56 52
DOI: https://doi.org/10.71637/tnhj.v26i3.1503

Maternal Information Needs of Pregnant Women: The Role of Medical Information Centres on Service Delivery

Adeyemi Adewale Akinola, David Dawi Mshelia, Adeniyi Michael Omotade, Koleayo Omoyajowo, Adedoyin Temilade Akinola

1329 – 1336

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208 66
DOI: https://doi.org/10.71637/tnhj.v26i3.1459

Pattern of Cervical Cytology among Hormonal Contraceptive Users and Non-Users in University of Port Harcourt Teaching Hospital, Nigeria 

Ebienju Walter Olaka, Okezie Chinedu Ugwa

1674 – 1680

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75 58
DOI: https://doi.org/10.71637/tnhj.v26i3.1549

Food Consumption Patterns in Relation to Adolescent Overweight and Obesity in Schools in A Semi Urban Area of Southwestern Nigeria

Omobola Oyebola Wopara, Dennis Kudu Egga, Grace Abosede Fayokun, Bright Ibeabughichi Nwaru

1099 – 1110

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211 45

Analysis of Microbiota at Different Topsoil Samples of Selected Site in Pandharpur Region

Mithun Maniyar, Jitendra Kandale, Anil Landge, Abhishek Meher

1471 – 1477

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38 51
DOI: https://doi.org/10.71637/tnhj.v26i3.1494

Antioxidant and Neuroprotective Effects of Echium amoenum Extract in a Sodium Valproate-Induced Mouse Model of Autism

Selman Mohammed Selman, Ameer Ali Al-Sherefy

1275 – 1281

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89 49
DOI: https://doi.org/10.71637/tnhj.v26i3.1453

Evaluation of the Antiulcer Potential and In-Vitro H⁺/K⁺-Atpase Inhibitory Activity of the Ethanolic Flower Extract of Saccharum Officinarum

Harshad Popat Khade, Digvijay Pruthviraj Patil, Anil Annaso Danane, Nikhil Dilip Patil, Ajay Rajaram Mali, Sangeeta Tukaram Sankpal, Shivani Sambhaji Khairmode, Rupali Prakash Lade

1599 – 1607

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40 52
DOI: https://doi.org/10.71637/tnhj.v26i3.1517

Therapeutic Potentials of Hepatitis B Virus Inhibitors from Annona Muricata, Jatropha Tanjerensis, and Phyllanthus Amarus: A Comparative Study of Bioactive Compounds and Drug Candidates

Clement Mboto, Ivon Akpang Ettah, Bassey Etta Agbo, Mathias Okang Ajaba, Solomon Iyam Offem, Godwin Michael Ubi, Eno Ebenso Eno, Samuel Effiong Udo, Henry Omoregie Egharevba, Ali Danjuma Zinoh, Wilfred Ndifon Okey, Iniobong Andy Effiong, John Ikpe Ugbadu, Bernard Okoro, Ignatius Omu Ejim, Blessing Ekanem Udoh, Chioma Blessing Ubah

1196 – 1214

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87 43
DOI: https://doi.org/10.71637/tnhj.v26i3.1439

Case Report and Series

Anaesthetic Management for Emergency Caesarean Section in A Severe Kyphoscoliotic Paturient with Severe Oligohydraminios: A Case Report

Fiekabo Hart, Onyeka Ijeoma Orji, Sotonye Fyneface-Ogan

1403 – 1408

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121 54
DOI: https://doi.org/10.71637/tnhj.v26i3.1478