Trial of Labour After Caesarean Section (TOLAC), Pattern, Outcome and Contemporary Predictors in A Tertiary-Level Obstetric Population in Southwest Nigeria: A Retrospective Descriptive Analysis
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Abstract
Background: The rising rate of caesarean section (CS) globally has led to an increasing population of women with uterine scars, necessitating evaluation of safe delivery options in subsequent pregnancies. Trial of labour after caesarean (TOLAC) offers an opportunity to achieve vaginal birth after caesarean (VBAC). However, its success and safety depend on careful patient selection and clinical factors. This study evaluated the pattern, outcomes, and predictors of TOLAC in a tertiary health facility.
Methods: This retrospective descriptive study was conducted at Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital, Ogbomoso, reviewing records of 292 women who underwent TOLAC between January 2020 and January 2025. Data were extracted from case notes and hospital registers using a structured tool. Descriptive statistics summarized variables, while chi-square tests assessed associations. Logistic regression identified independent predictors of VBAC success. Statistical significance was set at p<0.05.
Results: The VBAC success rate was 67.8%, while 32.2% had failed TOLAC. Significant predictors of successful VBAC included previous vaginal delivery (AOR=3.21), prior VBAC (AOR=4.05), Bishop score ≥6 (AOR=3.58), spontaneous labour (AOR=2.76), and booked pregnancy (AOR=2.14) (p<0.05). Maternal complications were relatively low. Neonatal outcomes were largely favourable, though 19.2% required Neonatal Intensive Care Unit (NICU) admission.
Conclusion: TOLAC demonstrated a high success rate with acceptable maternal and neonatal outcomes. Promoting carefully selected TOLAC, alongside adequate antenatal care and intrapartum monitoring, can reduce repeat caesarean sections and improve overall obstetric outcomes in similar settings.
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References
Betran AP, Ye J, Moller AB, Souza JP, Zhang J. Trends and projections of caesarean section rates: global and regional estimates. BMJ Glob Health. 2021;6(6).
Donati S, Fano V, Maraschini A; Regional Obstetric Surveillance System Working Group. Uterine rupture: results from a prospective population-based study in Italy. Eur J Obstet Gynecol Reprod Biol. 2021;264:70-75.
Rezai S, Labine M, Gottimukkala S, Karp S, Sainvil L. Trial of labor after cesarean (TOLAC) for vaginal birth after previous cesarean section (VBAC) versus repeat cesarean section: a review. Obstet Gynecol Int J. 2016;4(6):00135.
Familiari A, Neri C, Caruso A, Airoldi C, Barone-Adesi F, Zanconato G, et al. Vaginal birth after caesarean section: a multicentre study on prognostic factors and feasibility. Arch Gynecol Obstet. 2020;301(2):509-515.
Trojano G, Damiani GR, Olivieri C, Villa M, Malvasi A, Alfonso R, et al. VBAC: antenatal predictors of success. Acta Biomed. 2019;90(3):300-309.
Wingert A, Johnson C, Featherstone R, Sebastianski M, Hartling L, Wilson RD. Adjunct clinical interventions that influence vaginal birth after cesarean rates: systematic review. BMC Pregnancy Childbirth. 2018;18(1):452.
Wu Y, Kataria Y, Wang Z, Ming WK, Ellervik C. Factors associated with successful vaginal birth after a cesarean section: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2019;19(1):360.
Tegegne GA, Rade BK, Yismaw AE, Taye W, Mengistie BA. Predictors of successful trial of labor after cesarean section (TOLAC) in women with one prior transverse cesarean section at tertiary hospitals in northwest Ethiopia: a multicenter study. BMC Pregnancy Childbirth. 2024;24(1):240.
Ashwal E, Wertheimer A, Aviram A, Wiznitzer A, Yogev Y, Hiersch L. Prediction of successful trial of labor after cesarean: the benefit of prior vaginal delivery. J Matern Fetal Neonatal Med. 2016;29(16):2665-2670.
Nahum-Yerushalmy A, Walfisch A, Lipschuetz M, Rosenbloom JI, Kabiri D, Hochler H. Uterine rupture risk in a trial of labor after cesarean section with and without previous vaginal births. Arch Gynecol Obstet. 2022;305(6):1633-1639.
Carauleanu A, Tanasa IA, Nemescu D, Socolov D. Risk management of vaginal birth after cesarean section. Exp Ther Med. 2021;22(4):1111.
Tanos V, Toney ZA. Uterine scar rupture: prediction, prevention, diagnosis, and management. Best Pract Res Clin Obstet Gynaecol. 2019;59:115-131.
He X, Dai Q, Wu X, Zhou J, Li J. Outcomes and risk factors for failed trial of labor after cesarean delivery (TOLAC) in women with one previous cesarean section: a Chinese population-based study. BMC Pregnancy Childbirth. 2022;22(1):676.
Boatin AA, Cueto PD, Garba DL, Sawyer M, James K, Ngonzi J, et al. Trial of labour after caesarean section in Sub-Saharan Africa: a systematic review and meta-analysis. Reprod Female Child Health. 2024;3(3).
Bruno AM, Allshouse AA, Metz TD. Trends in attempted and successful trial of labor after cesarean delivery in the United States from 2010 to 2020. Obstet Gynecol. 2023;141(1):173-175.
Addisu D, Gebeyehu NA, Biru S, Belachew YY. Vaginal birth after cesarean section and its associated factors in Ethiopia: a systematic review and meta-analysis. Sci Rep. 2023;13(1):7882.
Kanjanakaew A, Jiramanee A, Srimoragot M. Providers' perspective on vaginal birth after cesarean birth: a qualitative systematic review. BMC Pregnancy Childbirth. 2024;24(1):723.
Li YX, Bai Z, Long DJ, Wang HB, Wu YF. Predicting the success of vaginal birth after caesarean delivery: a retrospective cohort study in China. BMJ Open. 2019;9(5).
Eleje GU, Okam PC, Okaforcha EI, Anyaoku CS. Rates and determinants of successful vaginal birth after a previous caesarean section: a prospective cohort study. ARC J Gynecol Obstet. 2019;4(2):1-8.
Mi Y, Qu P, Guo N, Bai R, Gao J, Ma Z, Luo X. Evaluation of factors that predict the success rate of trial of labor after the cesarean section. BMC Pregnancy Childbirth. 2021;21(1):527.
Mesay F, Melese E, Wudie G, Feleke SF, Dessie AM. A prognostic study for the development of risk prediction model for the success of vaginal birth following a cesarean surgery at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia. Risk Manag Healthc Policy. 2023;16:55-68.
Metz TD, Stoddard GJ, Henry E, Jackson M, Holmgren C, Esplin S. Simple, validated vaginal birth after cesarean delivery prediction model for use at the time of admission. Obstet Gynecol. 2013;122(3):571-578.
Michail A, Fasoulakis Z, Domali E, Daskalakis G, Antsaklis P. Role of the Bishop Score in Predicting Successful Induction of Vaginal Delivery: A Systematic Review of Current Evidence. Cureus. 2025;17(7).
Zhang HL, Zheng LH, Cheng LC, Liu ZD, Yu L, Han Q, et al. Prediction of vaginal birth after cesarean delivery in Southeast China: a retrospective cohort study. BMC Pregnancy Childbirth. 2020;20(1):538.
Parveen S, Rengaraj S, Chaturvedula L. Factors associated with the outcome of TOLAC after one previous caesarean section: a retrospective cohort study. J Obstet Gynaecol. 2022;42(3):430-436.
Afework B, Bekele M, Gizachew Y, Abebe S, Ajema D. Incidence and predictors of successful vaginal birth among women with a history of cesarean section in public health facilities of Southern Ethiopia in 2021. Int J Childbirth. 2024;14(1). doi:10.1891/IJC-2022-0125.