The Relationship between Body Mass Index, Pulse Rate and Intraocular Pressure
DOI:
https://doi.org/10.60787/tnhj.v24i4.869Keywords:
Body Mass Index (BMI), Pulse Rate, Intraocular Pressure, RelationshipAbstract
Background: Body mass index (BMI), pulse rate, and intraocular pressure (IOP) are key indicators of general well-being. This study investigated the relationship between these parameters of health to determine the effect of body mass index and pulse rate on intraocular pressure.
Method: The research involved 80 participants (44 males and 36 females) at the Nigeria Army Eye Centre in Bonny Camp, Lagos state. Assessments conducted include blood pressure, pulse rate, height, weight, and IOP. Blood pressure was measured with a Sphygmomanometer and a stethoscope to listen for Korotkoff sounds. Pulse rate was recorded by palpating the radial artery. Body weight was measured with a calibrated scale and height was measured using a meter rule attached to a wall. BMI was calculated by dividing the weight in kilograms by the height. IOP was assessed using a Pulsair non-contact tonometer. A One-Way analysis of Variance (ANOVA) was employed to analyze the data, with the use of the Statistical Package for Social Sciences (SPSS version 22.0).
Results: The results showed that IOP was significantly correlated with BMI (p = 0.011) and pulse rate (p = 0.000). However, pulse rate had a higher and more linear correlation with IOP. Multiple linear regression using IOP as dependent variable, and BMI, pulse rate and age as predictors, showed a statistically significant model (p = 0.000) with an R squared value of 51.4%. IOP was also significantly influenced by obesity as the mean IOP increased steadily across the different BMI weights groups: underweight (13.88 mmHg), normal weight (16.13mmHg), overweight (16.25mmHg), obese (17.00mmHg).
Conclusion: IOP increases with increasing BMI and is significantly different between underweight and obese normotensive subjects. Pulse rate has a stronger linear relationship with IOP than BMI and age, hence may be a better predictor of changes in intraocular pressure. It is advised to strictly monitor the intraocular pressure of individuals who are obese and individuals with abnormal pulse rates to prevent occurrences of high IOP.
Downloads
References
Reule S, Drawz PE. Heart rate and blood pressure: any possible implications for management of hypertension? Curr Hypertens Rep. 2012;14(6):478-84. doi: 10.1007/s11906-012-0306-3.
Birhanu G, Tegegne AS. Predictors for elevation of Intraocular Pressure (IOP) on glaucoma patients; a retrospective cohort study design. BMC Ophthalmol. 2022;22(1):254. doi: 10.1186/s12886-022-02431-w.
Nuttall FQ. Body Mass Index: Obesity, BMI, and Health: A Critical Review. Nutr Today. 2015;50(3):117-128. doi: 10.1097/NT.0000000000000092.
Machiele R, Motlagh M, Patel BC. Intraocular Pressure. [Updated 2022 Jul 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK532237/.
Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol. 1996;80(5):389-93. doi: 10.1136/bjo.80.5.389.
Chen HY, Lai SW. Relation between intraocular pressure and systemic health parameters in Taiwan. South Med J. 2005;98(1):28-32. doi: 10.1097/01.SMJ.0000145389.15201.7F.
Choudhary R, Gautam SC, Kumar J, Soni ND. Study of relationship between body mass index and intraocular pressure in western Rajastan. Indian Journal Appl Res. 2016;2(3):529-530.
British Heart Foundation. What is normal pulse rate[internet]. Available from: https://www.bhf.org.uk/informationsupport/heart-matters-magazine/medical/ask-the-experts/pulse-rate.
Mohajan D, Mohajan KS. Body Mass Index (BMI) is a Popular Anthropometric Tool to Measure Obesity in Adults. JIMR. 2023;2(4):2788-7022.
Leske MC, Connell AM, Wu SY, Hyman LG, Schachat AP. Risk factors for open-angle glaucoma. The Barbados Eye Study. Arch Ophthalmol. 1995;113(7):918-24. doi: 10.1001/archopht.1995.01100070092031.
Haslam DW, James WP. Obesity. Lancet. 2005;366(9492):1197-209. doi: 10.1016/S0140-6736(05)67483-1.
Aniket Inamdar, Association of body mass index with systolic and diastolic blood pressure in rural Indians. European Heart Journal. 2022;43(1)
https://doi.org/10.1093/eurheartj/ehab849.139
Jeong HR, Lee HS, Shim YS, Hwang JS. Positive Associations between Body Mass Index and Hematological Parameters, Including RBCs, WBCs, and Platelet Counts, in Korean Children and Adolescents. Children (Basel). 2022;9(1):109. doi: 10.3390/children9010109.
Guiraudou M, Varlet-Marie E, Raynaud de Mauverger E, Brun JF. Obesity-related increase in whole blood viscosity includes different profiles according to fat localization. Clin Hemorheol Microcirc. 2013;55(1):63-73. doi: 10.3233/CH-131690.
Sharfuddin Ahmed M, Ullah AY, Barman N, Ratan ZA, Mostafa S, Khaleque A, Kabir S, Khan MH, Haque MA. Risk factors associated with elevated intraocular pressure: a population-based study in a rural community of Bangladesh. BMJ Open Ophthalmol. 2023;8(1):e001386. doi: 10.1136/bmjophth-2023-001386. PMID: 37844969; PMCID: PMC10582991.
Ajayi OB, George GO. Relationship between body mass index, intraocular pressure, blood pressure and age in Nigerian population. Clinic Exp Ophthalmol. 2015; 6(4):1-5.
Mufti M, Nasti H, Shora T. Relationship between intraocular pressure and body mass index. Physiol Pharm Pharmacol 2019;9(6):540-542.
Pedro-Egbe CN, Awoyesuku EA, Nathaniel GI, Komolafe RO. The Relationship between Body Mass Index and Intraocular Pressure in Port Harcourt, Nigeria. Br J Med Med Res. 2013;3(3): 589-595,
Guyton AC, Hall JE. Textbook of Medical Physiology. 11th ed. Amsterdam: Elsevier Saunders; 2006.
Baisakhiya S, Singh S, Mushtaq F. Comparative Study of intraocular pressure and body mass index in North Indian Subjects. Intj J Med Health Sci. 2015;4(4).
Farnaz S, Saba AM, Darshan K. Relationship between body mass index and intraocular pressure in diabetic and hypertensive adults. Pak. J. Ophthalmol. 2016;32(1):4-8.
Coster D, Rafie A, Savion-Gaiger N, Rachmiel R, et al. The effect of body mass index reduction on intraocular pressure in a large prospective cohort of apparently healthy individuals in Israel. PLoS One. 2023 ;18(5):e0285759. doi: 10.1371/journal.pone.0285759.
Poonam GK, Harleen K, Seema M. Relation of body mass index with intraocular pressure. Indian J Basic Appl Med Res 2014;3(2):679-681.
Akinci A, Cetinkaya E, Aycan Z, Oner O. Relationship between intraocular pressure and obesity in children. J Glaucoma. 2007;16(7):627-30. doi: 10.1097/IJG.0b013e318057528a.
Ostry AS, Radi S, Louie AM, LaMontagne AD. Psychosocial and other working conditions in relation to body mass index in a representative sample of Australian workers. BMC Public Health. 2006; 6:53. doi: 10.1186/1471-2458-6-53.
Risner D, Ehrlich R, Kheradiya NS, Siesky B, McCranor L, Harris A. Effects of exercise on intraocular pressure and ocular blood flow: a review. J Glaucoma. 2009;18(6):429-36. doi: 10.1097/IJG.0b013e31818fa5f3.
Hong J, Zhang H, Kuo DS, Wang H, Huo Y, Yang D, Wang N. The short-term effects of exercise on intraocular pressure, choroidal thickness and axial length. PLoS One. 2014;29;9(8):e104294. doi: 10.1371/journal.pone.0104294.
Lee JS, Lee SH, Oum BS, Chung JS, Cho BM, Hong JW. Relationship between intraocular pressure and systemic health parameters in a Korean population. Clin Exp Ophthalmol. 2002;30(4):237-41. doi: 10.1046/j.1442-9071.2002.00527. x. PMID: 12121360.
Karadag R, Arslanyilmaz Z, Aydin B, Hepsen IF. Effects of body mass index on intraocular pressure and ocular pulse amplitude. Int J Ophthalmol. 2012;5(5):605-8. doi: 10.3980/j.issn.2222-3959.2012.05.12.
Albuquerque LL, Gaete MI, Figueiroa JN, Alves JG. The correlation between body mass index and intraocular pressure in children. Arq Bras Oftalmol. 2013 Jan-Feb;76(1):10-2. doi: 10.1590/s0004-27492013000100004. PMID: 23812519.
Karabatakis VE, Natsis KI, Chatzibalis TE, Lake SL, Bisbas IT, Kallinderis KA, Stangos NT. Correlating intraocular pressure, blood pressure, and heart rate changes after jogging. Eur J Ophthalmol. 2004;14(2):117-22. doi: 10.1177/112067210401400206.
Baek SU, Kee C, Suh W. Longitudinal analysis of age-related changes in intraocular pressure in South Korea. Eye (Lond). 2015;29(5):625-9. doi: 10.1038/eye.2015.11.
Yasukawa T, Hanyuda A, Yamagishi K, Yuki K, Uchino M, Ozawa Y, Sasaki M, Tsubota K, Sawada N, Negishi K, Tsugane S, Iso H. Relationship between blood pressure and intraocular pressure in the JPHC-NEXT eye study. Sci Rep. 2022;12(1):17493. doi: 10.1038/s41598-022-22301-1.
Bakke EF, Hisdal J, Semb SO. Intraocular pressure increases in parallel with systemic blood pressure during isometric exercise. Invest Ophthalmol Vis Sci. 2009;50(2):760-4. doi: 10.1167/iovs.08-2508.
Klein BE, Klein R, Knudtson MD. Intraocular pressure and systemic blood pressure: longitudinal perspective: the Beaver Dam Eye Study. Br J Ophthalmol. 2005;89(3):284-7. doi: 10.1136/bjo.2004.048710.
Wong TT, Wong TY, Foster PJ, Crowston JG, Fong CW, Aung T; SiMES Study Group. The relationship of intraocular pressure with age, systolic blood pressure, and central corneal thickness in an asian population. Invest Ophthalmol Vis Sci. 2009;50(9):4097-102. doi: 10.1167/iovs.08-2822. Epub 2009 May 20.
Gautam CS, Jayant K, Soni ND, Raguveer, C. (2016). Study of relationship between body mass index (BMI) and intra ocular pressure in western Rajasthan. Int J Appl Res. 2016;2(3): 529-530.
Mitchell P, Lee AJ, Wang JJ, Rochtchina E. Intraocular pressure over the clinical range of blood pressure: blue mountains eye study findings. Am J Ophthalmol. 2005;140(1):131-2. doi: 10.1016/j.ajo.2004.12.088.
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Atuanya GN, Erhumwun F, Ugwu IE, Obehi SI, Osaiyuwu AB
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The Journal is owned, published and copyrighted by the Nigerian Medical Association, River state Branch. The copyright of papers published are vested in the journal and the publisher. In line with our open access policy and the Creative Commons Attribution License policy authors are allowed to share their work with an acknowledgement of the work's authorship and initial publication in this journal.
This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author.
The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations. While the advice and information in this journal are believed to be true and accurate on the date of its going to press, neither the authors, the editors, nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.
TNHJ also supports open access archiving of articles published in the journal after three months of publication. Authors are permitted and encouraged to post their work online (e.g, in institutional repositories or on their website) within the stated period, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). All requests for permission for open access archiving outside this period should be sent to the editor via email to editor@tnhjph.com.