When a Deadly Disease Ironically becomes Desirable: Insights from 2023 Antimalarial Therapeutic Efficacy Studies in Nigeria

Authors

DOI:

https://doi.org/10.60787/tnhj.v24i3.879

Keywords:

Malaria, Nigeria, Therapeutic Efficacy Study

Abstract

Malaria continues to cause avoidable suffering and claims hundreds of lives annually, particularly in sub-Saharan Africa. The disease responds to antimalarials, but regular monitoring of the efficacy of the drugs and surveillance for parasite resistance are critical to having positive outcomes in case management. Nigeria, the country with the highest burden of the disease globally, conducted another antimalarial therapeutic efficacy studies (TES) in 2023 in four different zones in the country. Seeing the unusually pleasant way their children (study participants) were treated, caregivers’ perception of malaria as a deadly disease changed to that of a “desirable” malady. The clinical trial, done in a near-perfect environment, demonstrated that the disease is not indomitable after all. In this paper, we describe our experience at the trial and posit that, with a health system thinking approach and inclusive malaria interventions, Nigeria can overcome malaria and end mortality attributed to it soon

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References

World Health Organization. World Malaria Report 2023. Geneva; 2023.

WHO, CSDH. Closing the gap in a generation: health equity through action on the social determinants of health. 2008.

Ozawa S, Evans DR, Bessias S, Haynie DG, Yemeke TT, Laing SK, et al. Prevalence and Estimated Economic Burden of Substandard and Falsified Medicines in Low- And Middle-Income Countries: A Systematic Review and Meta-analysis. JAMA Netw Open. 2018;1(4):1–22.

Guissou RM, Amaratunga C, de Haan F, Tou F, Cheah PY, Yerbanga RS, et al. The impact of anti-malarial markets on artemisinin resistance: perspectives from Burkina Faso. Malar J. 2023;22(1):1–14.

Barasa E, Kazungu J, Nguhiu P, Ravishankar N. Examining the level and inequality in health insurance coverage in 36 sub-Saharan African countries. BMJ Glob Heal. 2021;6(4).

Ahmat A, Okoroafor SC, Kazanga I, Asamani JA, Millogo JJS, Illou MMA, et al. The health workforce status in the WHO African Region: findings of a cross-sectional study. BMJ Glob Heal. 2022;7.

Okedo-Alex IN, Akamike IC, Ezeanosike OB, Uneke CJ. Adherence to the test, treat and track strategy for malaria control among prescribers, Mfantseman Municipality, Central Region, Ghana. Int J Health Plann Manage [Internet]. 2019;34(4):e1387. Available from: http://dx.doi.org/10.1371/journal.pone.0279712

Beargie SM, Higgins CR, Evans DR, Laing SK, Erim D, Ozawa S. The economic impact of substandard and falsified antimalarial medications in Nigeria. PLoS One. 2019;14(8):1–16.

World Health Organization. Report on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010-2019). Geneva; 2020.

World Health Organization. T3: Test. Treat. Track: scaling up diagnostic testing, treatment and surveillance for malaria. 2012.

World Health Organization. Methods for surveillance of antimalarial drug efficacy. World Heal Organ [Internet]. 2009;90. Available from: https://apps.who.int/iris/bitstream/handle/10665/44048/9789241597531_eng.pdf?sequence=1%0Ahttp://www.who.int/malaria/publications/atoz/9789241597531/en/

Alliance for Health Policy and Systems Research, World Health Organization. Systems thinking for health system strengthening. Savigny D dey, Adam T, editors. 2009.

National Malaria Elimination Programme (NMEP) [Nigeria], (NPC) NPC, [Nigeria]. Nigeria Malaria Indicator Survey 2021 Final Report. Abuja, Nigeria, and Rockville, Maryland, USA: NPC and ICF.; 2022.

Anjorin ET, Olulaja ON, Osoba ME, Oyadiran OT, Ogunsanya AO, Akinade ON, et al. Overtreatment of malaria in the Nigerian healthcare setting; prescription practice, rationale and consequences. Pan Afr Med J. 2023;45.

Izevbekhai O, Adeagbo B, Olagunju A, Bolaji O. Quality of artemisinin-based antimalarial drugs marketed in Nigeria. Trans R Soc Trop Med Hyg. 2017;111(2):90–6.

National Malaria Elimination Programme. National Malaria Strategic Plan, 2021-2025 [Internet]. Abuja, Nigeria; 2020. Available from: https://nmcp.gov.ng/

World Health Organization. Global technical strategy for malaria 2016–2030. 2015;

Rosenthal PJ, Asua V, Bailey JA, Conrad MD, Ishengoma DS, Kamya MR, et al. The emergence of artemisinin partial resistance in Africa: how do we respond? Lancet Infect Dis [Internet]. 2024;3099(24):1–10. Available from: http://dx.doi.org/10.1016/S1473-3099(24)00141-5

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Published

2024-10-05

How to Cite

Oyeyemi, A. S., Ntadom, G., Olafisoye, K., Orimadegun, A., Ezeudu, C., Tsuung, A., … Falade, C. (2024). When a Deadly Disease Ironically becomes Desirable: Insights from 2023 Antimalarial Therapeutic Efficacy Studies in Nigeria. The Nigerian Health Journal, 24(3), 1617 – 1622. https://doi.org/10.60787/tnhj.v24i3.879

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Short Communication
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