Prevalence of Metabolic Syndrome and its Components in an Adult Nigerian Population attending a Tertiary Hospital

Authors

  • Norbert Ndubuisi Unamba Division of Cardiology Legacy Medical Consultants Ltd, Port Harcourt, Nigeria; ‘Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
  • Blessing C Unamba Division of Cardiology Legacy Medical Consultants Ltd, Port Harcourt, Nigeria; ‘Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.

DOI:

https://doi.org/10.60787/tnhj.v17i3.322

Keywords:

Metabolic Syndrome, Employees, Obesity, Insulin Resistance

Abstract

Background: The metabolic syndrome (Mets) is a clinical concept that comprises a cluster of risk factors like arterial hypertension, obesity and high cholesterol in the same patient. The prevalence of metabolic syndrome seems to increase together with the prevalence of obesity.

Objectives: To determine the prevalence of metabolic syndrome and related factors in an adult population in Nigeria.

Methods: This was a cross-sectional study that included 216 men and women. Sociodemographic, anthropometric, and biochemical characteristics were collected. Metabolic syndrome was diagnosed using the criteria of the National Cholesterol Education Program-ATPIIl (NCEP-ATP Ill). A logistic regression model was used to calculate the
crude odds ratio (OR) of the variables, and the Statistical level of significance was setat 5.0%. 

Results: We identified 62 (28.04%) subjects with metabolic syndrome according to the criteria of the NCEP-ATPIIl. More females had metabolic syndrome than males (38.8% vs. 15.3%, p<0.0001). MetS was associated positively with marital status and gender. Reduced HDL-C was found as the most common MetS component in our study (68.8%). Others in decreasing order were hypertension (66.7%), abdominal obesity (50.9%), high FBG levels (15.5%) and
hypertriglyceridemia (6.2%).

Conclusion: More female adults attending this tertiary healthcare facility have metabolic syndrome, which can be associated with an increased risk of developing cardiovascular disease. Individuals who were married had a
higher prevalence of metabolic syndrome; this finding can be explained by the high rate of obesity found in the married subjects. 

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References

Jaspinder Kaur. A Comprehensive Review on Metabolic Syndrome. Cardiology Research and Practice Volume 2014, Article ID 943162, 21 pages http://dx.doi.org/10.1155/2014/943162.

Paoletti R, Bolego C, Poli A, Cignarella A. Metabolic syndrome, inflammation and atherosclerosis. Vascular Health and Risk Management 2006:2(2) 145–152.

Jaspinder Kaur. Assessment and Screening of the Risk Factors in Metabolic Syndrome. Med. Sci. 2014, 2, 140-152; doi: 10.3390/medsci2030140.

Strauß M, Foshag P, Przybylek B, Horlitz M, Lucia A, et al. Occupation and metabolic syndrome: is there correlation? A cross sectional study in different work activity occupations of German firefighters and office workers. Diabetol Metab Syndr 2016; 8:57 DOI 10.1186/s13098-016-0174-0.

Arenillas JF, Moro MA, Dávalos A. The Metabolic syndrome and stroke: Potential treatment approaches. Stroke. 2007; 38:2196-2203.

Cho KL, Kim BH, Je HG, Jang JS, Park YH. Gender-Specific associations between socioeconomic status and psychological factors and metabolic syndrome in the Korean population: Findings from the 2013 Korean National Health and Nutrition Examination Survey. BioMed Research International Volume 2016, Article ID 3973197, 8 pages http://dx.doi.org/10.1155/2016/3973197.

Kassi E, Pervanidou P, Kaltsas G, Chrousos G. Metabolic syndrome: definitions and controversies. Kassi et al. BMC Medicine 2011, 9:48 http://www.biomedcentral.com/1741-7015/9/48.

Krishnadath ISK, Toelsie JR, Hofman AR, Jaddoe VWV. Ethnic disparities in the prevalence of metabolic syndrome and its risk factors in the Suriname Health Study: a cross-sectional population study. BMJ Open 2016; 6:e013183. Doi: 10.1136/bmjopen-2016-013183.

Santos AC, Ebrahim S, Barros H. Gender, socio-economic status and metabolic syndrome in middle-aged and old adults. BMC Public Health 2008, 8:62 doi: 10.1186/1471-2458-8-62.

Espelta A, Borrella C, Palènciaa L, Godaye A, Spadeaf T , et al. Socioeconomic inequalities in the incidence and prevalence of type 2 diabetes mellitus in Europe. Gac Sanit. 2013; 27(6):494–501.

Moreira GC, Cipullo JP, Ciorlia LAS, Cesarino CB, Vilela-Martin JF. Prevalence of Metabolic Syndrome: Association with Risk Factors and Cardiovascular Complications in an Urban Population. PLoS ONE 9(9): e105056. doi:10.1371/journal.pone.0105056.

Perel P, Langenberg C, Ferrie J, Moser K, Brunner E, et al. Household wealth and the metabolic syndrome in the Whitehall II Study. Diabetes Care 29:2694 –2700, 2006.

Al-Daghri NM, Alkharfy KM, Al-Attas OS, Khan N, Alfawaz HA, et al. Gender-dependent associations between socioeconomic status and metabolic syndrome: a cross-sectional study in the adult Saudi population. BMC Cardiovascular Disorders 2014, 14:51 http://www.biomedcentral.com/1471-2261/14/51.

Smith L, McCourt O, Sawyer A, Ucci M, Marmot A, et al. A review of occupational physical activity and sedentary behavior correlates. Occupational Medicine 2016; 66:185–192 doi:10.1093/occmed/kqv164.

Silventoinen K, Pankow J, Jousilahti P, Hu G, Tuomilehto J. Educational inequalities in the metabolic syndrome and coronary heart disease among middle-aged men and women. International Journal of Epidemiology 2005; 34:327–334.

Houti L, Hamani-Medjaoui I, Lardjam-Hetraf SA, Ouhaibi-Djellouli H, Chougrani S, et al. Prevalence of metabolic syndrome and its related risk factors in the City of Oran, Algeria: the ISOR Study. Ethn Dis. 2016; 26(1):99-106; doi: 10.18865/ ed.26.1.99.

Wnkleby MA, Jatulis DE, Frank E, Fortmann SP. Socioeconomic status and health: How education, income, and occupation contribute to risk factors for cardiovascular disease. Am J Public Health 1992; 82: 816-820.

Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, et al. Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005, 112, 2735–2752.

Freidewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of preparative ultracentrifugation. Clin Chem 1972; 18: 499-502.

Oguoma VM, Nwose EU, Richards RS. Prevalence of cardio-metabolic syndrome in Nigeria: a systematic review. Public Health 2015; 129: 413-423.

Akintunde AA, Ayodele OE, Akinwusi PO, Opadijo GO. Metabolic syndrome: comparison of occurrence using three definitions in hypertensive patients. Clin Med Res. 2011; 9(1): 26-31.

Osuji CU, Omejua EG. Prevalence and characteristics of the metabolic syndrome among newly diagnosed hypertensive patients. Indian J Endocr Metab 2012; 16:S104-109.

Siminialayi IM, Emem-Chioma PC. Metabolic syndrome in a rural Nigerian community: Is central obesity always the key determinant? The Nigerian Health Journal 2008; 8: 48-51.

Celermajer DS, Chow CK, Marijon E, Anstey NA, Woo KS. Cardiovascular Disease in the Developing World: Prevalences, patterns, and the potential of early disease detection. JACC 2012; 60: 1207–1216.

Lee S, Ko Y, Kwak C, Yim E-S. Gender differences in metabolic syndrome components among the Korean 66-year-old population with metabolic syndrome. BMC Geriatrics 2016; 16:27 DOI 10.1186/s12877-016-0202-9.

Bener A, Mohammad A-G, Ismail AN, Zirie M, Abdullatef WK, et al. Gender and age-related differences in patients with the metabolic syndrome in a highly endogamous population. Bosnian Journal of Basic Medical Sciences 2010; 10 (3): 210-217.

Gharipour M, Sadeghi M , Nouri F, Nezafati P, Qader SS, et al. Socioeconomic determinants and metabolic syndrome: results from the Isfahan Healthy Heart Program. Acta Biomed 2016; 3: 291-298.

Ikeda A , Iso H, Toyoshima H, Fujino Y, Mizoue T, et al. Marital status and mortality among Japanese men and women: the Japan Collaborative Cohort Study. BMC Public Health 2007, 7:73 doi: 10.1186/1471-2458-7-73.

Joung IM, Stronks K, van de Mheen H, Mackenbach JP. Health behaviours explain part of the differences in self reported health associated with partner/marital status in The Netherlands. J Epidemiol Community Health 1995, 49(5):482-488.

Bhanushali CJ, Kumar K, Wutoh AK, Karavatas S, Habib MJ, et al. Association between Lifestyle Factors and Metabolic Syndrome among African Americans in the United States. Journal of Nutrition and Metabolism Volume 2013, Article ID 516475, 6 pages http://dx.doi.org/10.1155/2013/516475.

Troxel WM, Matthews KH, Gallo LC, Kuller LH. Marital quality and occurrence of the metabolic syndrome in women. Archives of Internal Medicine 2005; 9: 1022– 1027.

Sabir AA, Jimoh A, Iwuala SO, Isezuo SA, Bilbis LS, et al. Metabolic syndrome in urban city of North-Western Nigeria: Prevalence and determinants. Pan African Medical Journal 2016; 23:19 doi:10.11604/pamj.2016.23.19.5806.

Onyenekwu CP, Dada AO, Babatunde OT. The prevalence of metabolic syndrome and its components among overweight and obese Nigerian adolescents and young adults. Niger J Clin Pract 2017; 20:670-676.

Nwegbu MM, Jaiyesimi OO. Prevalence of metabolic syndrome amongst apparently healthy Nigerian adults in a hospital setting. Journal of Medicine and Medical Sciences 2012; 3(1): 77-82.

Zhan Y , Yu J, Chen R, Gao J, Ding R, et al. Socioeconomic status and metabolic syndrome in the general population of China: a cross-sectional study. l. BMC Public Health 2012, 12:921 http://www.biomedcentral.com/1471-2458/12/921.

Thurston RC, Kubzansky LD, Kawachi I, Berkman LF: Is the association between socioeconomic position and coronary heart disease stronger in women than in men? Am J Epidemiol 2005, 162(1):57–65.

Pampel FC, Krueger PM, Denney JT. Socioeconomic Disparities in Health Behaviors. Annu Rev Sociol. 2010; 36: 349–370.

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Published

2018-03-04

How to Cite

Unamba, N. N., & Unamba , B. C. (2018). Prevalence of Metabolic Syndrome and its Components in an Adult Nigerian Population attending a Tertiary Hospital. The Nigerian Health Journal, 17(3), 105–118. https://doi.org/10.60787/tnhj.v17i3.322
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