Factors Associated with Treatment Success among Pulmonary Tuberculosis and HIV Co-infected Patients in Oyo State, South West-Nigeria

Authors

  • Olanrewaju Oladimeji Management Sciences for Health/Center for Health Services, Abuja-Nigeria and Department of Epidemiology and Medical Statistics, University of lbadan, Ibadan
  • Joshua Obasanya National Tuberculosis and Leprosy Control Program, Ministry of Health, Abuja
  • Olusoji Daniel World Health Organisation, TUB, Nigeria,
  • Mustapha Gidado World Health Organisation, TUB, Nigeria and 4KNCV / TB CARE 1, Abuja, Nigeria
  • Christopher Akolo Nigeria, institute of Human Virology, Abuja
  • Kelechi Oladimeji Department of Epidemiology and Medical Statistics, University of lbadan, Ibadan
  • Olayinka Atilola University College Hospital, Ibadan-Nigeria
  • Temitope Ajayi University College Hospital, Ibadan-Nigeria
  • Adedayo Adeyinka HIV Division of Federal Ministry of Health, Abuja
  • Eltayeb Osman Damien Foundation Belgium, Nigeria Project, Ibadan
  • Temitayo Odusote United State Agency for International Development, Abuja
  • Ayodele Awe World Health Organisation, TUB, Nigeria
  • Oyewole Lawal Tuberculosis and Leprosy Control Program, Oyo State Ministry of Health, Ibadan
  • Amos Omoniyi World Health Organisation, TUB, Nigeria
  • David Dairo Damien Foundation Belgium, Nigeria Project
  • Babatunde Adedokun Department of Epidemiology and Medical Statistics, University of lbadan, Ibadan
  • Ikeola Adeoye Department of Epidemiology and Medical Statistics, University of lbadan, Ibadan
  • Franklin Igodekwe Department of Epidemiology and Medical Statistics, University of lbadan, Ibadan
  • Abiodun Hassan Association for Reproductive Health ,Abuja-Nigeria
  • Matthew Onoja Department of Epidemiology and Medical Statistics, University of lbadan, Ibadan

Keywords:

Tuberculosis, Human immunodeficiency virus, Directly observe therapy short-course, Treatment success, Co- infection.

Abstract

The co-existence of Tuberculosis (TB) and Human immunodeficiency Virus (HIV) is known to increase morbidity and mortality in patients. The determinants of treatment success in TB- HIV co-infection are not yet well studied. Such information can help optimise treatment and reduce morbidity and mortality. The objective of this study was to determine factors associated with anti- tubercular treatment success among TB /HIV co- infected patients.

METHODS

A cross sectional study was carried out in fifty three DOT clinics and treatment centres using tuberculosis patient's records from January 2009 to December 2010 in Oyo state, Nigeria. The study population consisted of 7905 tuberculosis patients. Information on variables of interest were obtained with the use of data extraction forms. Chi-square and logistic regression were used to test the relationship between TBI HIV co- infection and socio-demographic variables, clinical characteristics and treatment success.

RESULTS

Prevalence of TB /HTV co-infection was found to be 14.2%. Patients with TB-HTV co-infection were younger and more likely to be females. There were statistically significant association between treatment success and gender, marital status and patient point of care. After adjusting for other variables, it was found that patients receiving treatment in private facilities were independently less likely to be successfully treated compared with those receiving care in Public facilities. Female patients were also independently more likely to have better treatment outcome than male.

CONCLUSION

In addition to patients ‘point of care, gender of the patients can adversely impact on their treatment success. Efforts from the government to strengthening the private public mix, health education and media awareness on adherence to treatment to improve treatment success should be intensified in the country

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Published

2015-12-10

How to Cite

Oladimeji, O., Obasanya, J., Daniel, O., Gidado, M., Akolo, C., Oladimeji, K., Atilola, O., Ajayi, T., Adeyinka, A., Osman, E., Odusote, T., Awe, A., Lawal, O., Omoniyi, A., Dairo, D., Adedokun, B., Adeoye, I., Igodekwe, F., Hassan, A., & Onoja, M. (2015). Factors Associated with Treatment Success among Pulmonary Tuberculosis and HIV Co-infected Patients in Oyo State, South West-Nigeria. The Nigerian Health Journal, 13(2), 75. Retrieved from https://tnhjph.com/index.php/tnhj/article/view/95

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Original Articles