Bacterial Profile and Antimicrobial Susceptibility pattern of Nosocomial Wound Infection in a Teaching Hospital at Uyo, Akwa Ibom State, Nigeria

Ifeanyi Abraham Onwuezobe


Background. Nosocomial wound infection has been implicated to occur globally. There are various types of wounds some of which may be peculiar to the environment, occupation and social life of the people. Postoperative wound infection is common in hospital and is spread directly from person to person or indirectly from equipment or personal care items. They are a significant burden to patients and public health and also a major cause of increased morbidity in hospitalized patients. Objective. This study was aimed to determine  the bacterial agents and antimicrobial susceptibility pattern of organisms causing nosocomial wound infection in the University of Uyo Teaching Hospital (UUTH), Uyo. Methodology. A cross sectional study was carried out by collecting wound swab samples from 170 patients in different wards in the hospital. Result. Staphylococcus aureus (28.7%) was mostly isolated while, Pseudomonas aeruginosa (22.9%) was the most isolated Gram negative bacterial agent from the wound sites. The antimicrobial susceptibility pattern revealed increased sensitivity of S. aureus to gentamicin (70%), while Pseudomonas aeruginosa was most sensitive to Imipenem (90%). More than 40% of the Staphylococcus aureus were methicillin resistant and among the Gram negative bacterial agents isolated were extended beta lactamase producers. Conclusion. There is need therefore for routine check and reporting of methicillin resistant Staphylococcus and extended spectrum beta lactamase producers from wound isolates by all tertiary hospitals in Akwa Ibom state in particular and Nigeria by extension.


Nosocomial, wound infection, bacteria, antibiotic profile



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