Bacterial Profile and Antimicrobial Susceptibility pattern of Nosocomial Wound Infection in a Teaching Hospital at Uyo, Akwa Ibom State, Nigeria
DOI:
https://doi.org/10.60787/tnhj.v16i4.246Keywords:
Nosocomial, wound infection, bacteria, antibiotic profileAbstract
Background. Nosocomial wound infection has been implicated to occur globally. There are various types of wounds some of which may be peculiar to the environment, occupation and social life of the people. Postoperative wound infection is common in hospital and is spread directly from person to person or indirectly from equipment or personal care items. They are a significant burden to patients and public health and also a major cause of increased morbidity in hospitalized patients.
Objective. This study was aimed to determine the bacterial agents and antimicrobial susceptibility pattern of organisms causing nosocomial wound infection in the University of Uyo Teaching Hospital (UUTH), Uyo.
Methodology. A cross sectional study was carried out by collecting wound swab samples from 170 patients in different wards in the hospital.
Result. Staphylococcus aureus (28.7%) was mostly isolated while, Pseudomonas aeruginosa (22.9%) was the most isolated Gram negative bacterial agent from the wound sites. The antimicrobial susceptibility pattern revealed increased sensitivity of S. aureus to gentamicin (70%), while Pseudomonas aeruginosa was most sensitive to Imipenem (90%). More than 40% of the Staphylococcus aureus were methicillin resistant and among the Gram negative bacterial agents isolated were extended beta lactamase producers.
Conclusion. There is need therefore for routine check and reporting of methicillin resistant Staphylococcus and extended spectrum beta lactamase producers from wound isolates by all tertiary hospitals in Akwa Ibom state in particular and Nigeria by extension.
Downloads
References
Bowler PG, Duerden BI, Armstrong DG. Wound Microbiology and Associated Approaches to Wound Management. Clin Microbiol Rev. 2001; 14: 244-269.
Coffin SE, Zaoutis TE. Infection Control, Hospital Epidemiology and Patient Safety. Clin Infect Dis. 2005; 19:647-665.
Dionigi R, Rovera F, Dionigi G, Imperatori A, Ferrari A, Dominion I. Risk Factors in Surgery. J. Chemo. 2001; 13:6-11.
Klevens RM, Edward J R, Richards C. Estimating Health Care Associated Infections and Deaths in U.S. Hosp Pub Health Rep. 2007; 122(2): 160-6.
Samuel SO, Kayode OO, Musa OI, Nwigwe GC, Aboderin AO, Salami TAT, et. al. Nosocomal infections and the challenges of control in development countries. African J Clin Exp Microbiol. 2010; 11 (2):102-110.
Iroha IR, Amadi ES, Orji JO, Esimone CO. In Vitro Evaluation of the Activity of Colloidal Silver Concentrate Against Pseudomonas aeruginosa Isolated from Postoperative Wound Infection. Sci Res Essay. 2008; 3(5): 209-211.
Oguntibeju OO, Nwobu RAU. Occurrence of Pseudomonas aeruginosa in Post Operative Wound Infection. Pakistan J Med Serv. 2004; 20(30), 187-191.
Cheesbrough M. Morphology and Characterization of Esherichia coli and Staphylococcus aureus. District Laboratory Practice in Tropical Countries Part II, Hong Kong: Sheck Wah Tong Printing Press Limited. 2004; pp. 63-70.
CLSI. Performance Standards for Antimicrobial Disk Susceptibility Tests. CLSI Approved Standard M100-S17. Wayne, P. A.: Clinical and Laboratory Standard Institute 2006; pp.72- 81.
CLSI. Performance Standards for Antimicrobial Susceptibility Test. CLSI Approved Standard M100-S17. Wayne, P. A.: Clinical and Laboratory Standard Institute. 2011; pp.72- 81.
Horan TC, Gaynes RP. Surveillance of Nosocomial Infections. In: Hospital Epidemiology and Infection Control 3rd ed., Mayhall C.G (ed). Philadelphia Lippincourtt.: Williams and Wilkins.
; pp. 1659-1702.
Abbey SD, Ayodele MBO, Nwokah EG, Obunge OK, Omakwele GCS. Microbial Profile of Wound Infections In Nigerian Teaching Hospital. Port Harcourt: Department of Medical Laboratory Science, Rivers State University of Science and Technology, Port Harcourt, Nigeria. 2010; pp. 5-11.
Ranjan K, Prabhat RN, Satish KB, Arora DR. Prevalence of Pseudomonas aeruginosa in Post-Operative Wound Infection in a Referral Hospital in Haryana. India J Hospital Infec. 2011; 3(2):129.
Buwembo, KBM. Post Operative Wound Infections. Kampala Makerere University 1990; pp. 1-45.
Anguzu JR, Olila D. Drug Sensitivity Patterns of Bacterial Isolates from Septic Post-operative Wounds in a Regional Referral Hospital in Uganda. J African Health Sci. 2007: 7(3): 148-154.
Ranjan K, Prabhat RN, Satish KB, Arora DR. Prevalence of Pseudomonas aeruginosa in Post-Operative Wound Infection in a Referral Hospital in Haryana, India. Journal of Hospital Infection. 2011; 3(2):129.
Navaneeth KY, Pooja S, Ankur O, Shruti P, Singh RK. Next Generation Sequencing. Potential and Application in Drug Discovery. Sci World J. 2013; 7,437 – 438.
WHO. Basic Laboratory Procedure in Clinical Bacteriology. 1991; pp. 62-64.
Ramesh N, Sumath CS, Balasubramanian VK, Palaniappan KR, Kannan VR. Urinary Tract Infection and Antimicrobial Susceptibility Pattern of ESBL Producing Clinical Isolates. Adv Bio Res. 2008; 2(5-6): 78-82.
Ahmed MI. Prevalence of Nosocomial Wound Infection Among Postoperative Patients and Antibiotics Patterns at Teaching Hospital in Sudan. Am J Med Sci. 2012; 4(1): 29–34.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2017 The Nigerian Health Journal
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The Journal is owned, published and copyrighted by the Nigerian Medical Association, River state Branch. The copyright of papers published are vested in the journal and the publisher. In line with our open access policy and the Creative Commons Attribution License policy authors are allowed to share their work with an acknowledgement of the work's authorship and initial publication in this journal.
This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author.
The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations. While the advice and information in this journal are believed to be true and accurate on the date of its going to press, neither the authors, the editors, nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.
TNHJ also supports open access archiving of articles published in the journal after three months of publication. Authors are permitted and encouraged to post their work online (e.g, in institutional repositories or on their website) within the stated period, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). All requests for permission for open access archiving outside this period should be sent to the editor via email to editor@tnhjph.com.
