Prevalence of Human Rhinovirus Infection in Children with Acute Respiratory Symptoms in Ilorin, Nigeria
DOI:
https://doi.org/10.60787/tnhj.v15i2.213Keywords:
Rhinovirus, ELISA, prevalence, risk factors, Human RhV-Ag, IlorinAbstract
Background: Human rhinoviruses are positive-strand RNA, non-enveloped virus detected mostly in the early phase of infection showing symptoms in children experiencing mild upper respiratory tract infections.
Method: In this study, 200 patients were screened for rhinovirus infection using Human Rhinovirus antigen (RhV-Ag) Elisa Kit (MBS269914).
Result: Demographic characteristics revealed that the prevalence of rhinovirus infection in children showed 38% positivity of which 20 (10.0%) were males while 17 (8.5%) were females. Children between the ages of 0-24 months have the highest prevalence of 45.9% while those older than 96 months have the least prevalence of 5.4%. No significant difference was observed between the genders and rhinovirus infection (p = 0.622). A total of 54.0%, 2.7%, 29.7% and 13.5% of the children attend daycare, creche, nursery and primary school respectively. A total of 140 (70%) in the urban recorded a positivity value of 11.0% and 59.0% negativity as against 60 (30%) who lived in the rural area with a value of 7.5%positivity and 22.5% negativity. Forty (20.0%) of the tested subjects had genotype AA out of which 6 (3.0%) was positive for rhinovirus infection, the remaining 34 (17.0%) were negative for the rhinovirus infection.
Conclusion: This study established the detection of rhinovirus infection in children attending the pediatrics clinic in Ilorin. This may become useful for diagnosing respiratory illness in high-risk populations with immune compromised individuals.
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