Malaria/HIV interactions in Nigeria - A review
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Abstract
Background: Malaria and HIV are two of the most common and important health problems facing developing countries and Nigeria being the most populous African country bears a very high percentage of this burden. This article is an attempt to review the published articles on the co- infection of the two diseases available in literature from Nigeria.
Methods: A review of the literature on the subject was done utilizing google search, Medline, PubMed and other available literature. The keywords were Malaria and HIV; Interactions and Nigeria.
Results: Malaria and HIV constitute major public health threats responsible for significant morbidity and mortality in the country. Malaria and HIV are diseases of poverty resulting in over 4 million deaths a year. Both diseases are highly endemic, with a wide geographic overlap in sub-Saharan Africa and Nigeria. The management of the co-infection is a major challenge to the public health system. Of particular importance is the potential drug-drug interactions involved in the management of the co-infections as a result of coadministration of the drugs which have not been adequately investigated.
Conclusion: Despite the endemicity of both diseases in Nigeria, there is paucity of data on the interaction of the two diseases.
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