Vitiligo: any differences in adult and childhood clinical characteristics
DOI:
https://doi.org/10.60787/tnhj.v18i3.374Keywords:
Vitiligo, Adult/Childhood Differences, Clinical CharacteristicsAbstract
Background: Vitiligo occurs in both children and adults, average age of onset is before twenty years in at least half of adult cases and five years in children. In Nigeria, there are relatively few literatures specifically comparing clinical characteristic between adult and childhood vitiligo in order to identify any differences in our environment as elsewhere.
Aims and Objectives: The objectives were to identify any differences in clinical characteristics between childhood and adult vitiligo.
Methodology: A record based review of clinical characteristics of one hundred and one vitiligo patients at the out-patient clinic from 2005 to 2009 was conducted. Socio-demographic variables were assessed using a structured questionnaire.
Results: Prevalence of vitiligo was 6.5%. Of the 111cases retrieved, 68.5% were adults and 31.5% were children. Significant differences between adult and childhood vitiligo include; preponderance of females in childhood vitiligo (34.3% males versus 65.7% females) and of males in adult vitiligo (57.9% males versus 42.1% females). Re-pigmentation of lesions following treatment was more in children (82.4% versus 56.7% in adults). Reported history of spread of lesions was 72.7% in children and 49.2% in adults. Commonest class of vitiligo is segmental in childhood study population (45.7%) and acrofacial in adults (36%). The vulva as area of onset was observed only in children.
Conclusion: Significant differences in clinical characteristics between adult and childhood vitiligo exist. These include; gender, re-pigmentation, spread of lesions and class of vitiligo. Only children have the vulva as the area of onset of vitiligo.
Downloads
References
De Barros JC, Filho CDSM, Abreu LC, De Barros JA, Paschoal FM, Nomura MT, Marques E, Martins LC. A study of Clinical Profiles of Vitiligo in Different Ages: An Analysis of 669 Outpatients. Int. J. Dermatol. 2014;53:842-848.
Solak B, Dikicier BS, Cosansu NC, Erdem T. Effects of Age of Onset on Disease Characteristics in Non-segmental Vitiligo. Int. J. Dermatology 2017;56:341-345.
Agarwal S, Gupta S, Ojha A, Sinha R. Childhood Vitiligo: Clinicoepidemiologic Profile of 268 Children from the Kumaun Region of Uttarakhand, India. Pediatr Dermatol. 2013;30:348-53.
Herane MA. Vitiligo and Leucoderma in Children. Clinics In Dermatol 2003;12:283-295.
Mulekar SV, Al Eisa A, Delvi MB, Al Issa A, Al Saeed AH. Childhood Vitiligo: A Long-term Study Of Localized Vitiligo Treated By Noncultured Cellular Grafting. Pediatr. Dermatol. 2010;27:132-136.
Kakourou T. Vitiligo In Children. World J Pediatr.2009;5:265-268.
Jaisankar TJ, Barauh MK, Garg BT. Vitiligo In Children. Int. J Dermatol.. 1992;31:621-623.
Pajvani U, Ahmad N, Wiley A, Levy RM, Kundu R, Mancim AJ et al. The Relatonship Between Family Medical History And Chilhood Vitiligo. Journal of the American Academy of Dermatology. 2006;55: 238-244.
Oninla OA, Oninla SO, Onayemi O, Olasode OA. Pattern of Paediatric Dermatoses at Dermatology Clinics in Ile-Ife and Ilesha, Nigeria. Paediatr Int Child Health. 2016;36:106-12
Ayanlowo O, Olumide YM, Akinkugbe A, Ahamneze N, Otike-Odibi BI, Ekpudu VI, Nnaji T, Akolawole NA. Characteristics of vitiligo in Lagos, Nigeria. West Afr J Med. 2009;28:118-21.
Onunu AN, Kubeyinje EP. Vitiligo In The Nigerian African: A Study Of 351 Patients. Int J Dermatol 2003;42:800-802.
Nicolaidou E, Antoniou C, Miniati A, Lagogianni E, Matekovits A, Stratigos A, Katsambas A. Childhood- and Later-onset Vitiligo Have Diverse Epidemiologic and Clinical Characteristics. J Am Acad Dermatol 2012;66:954-8.
Nordlund JJ, L erner AB. Vitiligo: It Is Important. Arch.Dermatol. 1982;118:5-8.
Statistical Package For Social Sciences (SPSS) Version 15.0 For Windows; Released 2006. Chicago:SPSS Inc.
Al-Mutari N, Sharma AK, Al-Sheltawy M, Nour-Eldin O. Childhood Vitiligo: A Prospective Hospital-Based Study. Australian Journal of Dermatology. 2005;46: 150-155.
Cho S, Kang H-C, Hahm J-H. Characteristics of Vitiligo in Korean Children Pediatric Dermatology. 2000;17:189-193.
Passeron T, Ortone JP. Physiopathology and Genetics of Vitiligo. Journal of Auto-immunity. 2005;25:63-68.
Handa S, Dogra S. Epidemiology Of Childhood Vitiligo: A Study Of 625 Patients From North India. Pediatr. Dermatol. 2003;20:207-210.
Paravar T, Lee DJ. Vitiligo In An Urban Academic Setting. Int. J Dermatol. 2010;49;39-43.
Kruger C, Schallreuter KU. A Review of the Worldwide Prevalence of Vitiligo in Children/Adolescents and Adults. Int. J. Dermatol. 2012;51:1206–1212.
Halder RM, Brooks HL. Medical Therapies for Vitiligo. Dermatologic therapy. 2001;14:1-6.
Van Geel N, Ongenae K, Naeyaert JM. Surgical Techniques for Vitiligo: a Review. Dermatology 2001; 202:162–166.
Wolf R, Wolf D, Ruocco E, Brunetti G, Ruocco V. Wolf's Isotopic Response. Clin Dermatol.2011;29:237-40.
Happle R, Kluger N. Koebner's Sheep in Wolf's Clothing: Does the Isotopic Response Exist as a Distinct Phenomenon? J Eur Acad Dermatol Venereol. 2018;32:542-543.
Parsad D, Handa S, Kanwar AJ. Late onset Vitiligo : A Study of 182 patients. Int. J. Dermatol. 2005;440:193-196.
Alenizi DA. Consanguinity pattern and heritability of Vitiligo in Arar, Saudi Arabia. J Family Community Med. 2014;21: 13-16.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 The Nigerian Health Journal
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The Journal is owned, published and copyrighted by the Nigerian Medical Association, River state Branch. The copyright of papers published are vested in the journal and the publisher. In line with our open access policy and the Creative Commons Attribution License policy authors are allowed to share their work with an acknowledgement of the work's authorship and initial publication in this journal.
This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author.
The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations. While the advice and information in this journal are believed to be true and accurate on the date of its going to press, neither the authors, the editors, nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.
TNHJ also supports open access archiving of articles published in the journal after three months of publication. Authors are permitted and encouraged to post their work online (e.g, in institutional repositories or on their website) within the stated period, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). All requests for permission for open access archiving outside this period should be sent to the editor via email to editor@tnhjph.com.