Review of Histological Variants of Uterine Leiomyomas seen in a Teaching Hospital
Histological Variants of Uterine Leiomyomas
DOI:
https://doi.org/10.60787/tnhj.v24i3.885Keywords:
Leiomyoma, degenerations, histological, variant, fibroidsAbstract
Background: Uterine leiomyoma is the commonest benign smooth muscle tumour of unknown aetiology and occurs mostly in reproductive-age women. The gross appearances are often altered by various degenerative changes and histological types of leiomyomas are of mainly interest as they may mimic malignancy in rare cases. This study described histopathological variants and degenerative changes of uterine leiomyomas seen at LTH, Ogbomoso over a 5- year.
Method: This was a hospital based retrospective study of 192 cases of uterine leiomyoma diagnosed histologically at the Department of Morbid Anatomy LTH, Ogbomoso between January 2012 and December 2016. Cases were retrieved from the histopathology register and demographic characteristics such as age were extracted. Leiomyomas were classified using 2014 edition of World Health Organization Classification of Uterine Smooth Muscle Tumour. Data obtained was analysed using both Microsoft Excel and Statistical Package for Social Sciences 23.0 (SPSS version 23.0).
Result: Leiomyoma was commonly seen the fourth decade of life which accounted for about 40.6%. Multiple nodules were found in 136(70.8%) cases. Intramural leiomyoma was the most common site accounting for 176(91.7%) cases. Usual leiomyoma was the commonest histological type accounting for 182(94.8%) cases. Degenerative changes were seen in 124 (64.6%) cases and hyaline change was the commonest secondary change with a frequency of 115 (59.9%).
Conclusion: Majority of women with uterine leiomyomas presented with multiple nodules. Intramural site was the most common location. Hyaline change was the most common degeneration and usual variant was the most common subtype seen in our study.
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