Prevalence of Human Rhinovirus Infection in Children with Acute Respiratory Symptoms in Ilorin, Nigeria

Authors

  • Olatunji Matthew Kolawole Infectious Diseases and Environmental Health Research Group, Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin
  • Busayo Joseph Adeyemi Infectious Diseases and Environmental Health Research Group, Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin
  • Aishat Abdulrahman Gobir Department of Paediatrics, University of Ilorin, Ilorin

Keywords:

Rhinovirus, ELISA, prevalence, risk factors, Human RhV-Ag, Ilorin

Abstract

Background: Human rhinoviruses are positive-strand RNA, non-enveloped virus detected mostly in the early phase of infection showing symptoms in children experiencing mild upper respiratory tract infections.

Method: In this study, 200 patients were screened for rhinovirus infection using Human Rhinovirus antigen (RhV-Ag) Elisa Kit (MBS269914).

Result: Demographic characteristics revealed that the prevalence of rhinovirus infection in children showed 38% positivity of which 20 (10.0%) were males while 17 (8.5%) were females. Children between the ages of 0-24 months have the highest prevalence of 45.9% while those older than 96 months have the least prevalence of 5.4%. No significant difference was observed between the genders and rhinovirus infection (p = 0.622). A total of 54.0%, 2.7%, 29.7% and 13.5% of the children attend daycare, creche, nursery and primary school respectively. A total of 140 (70%) in the urban recorded a positivity value of 11.0% and 59.0% negativity as against 60 (30%) who lived in the rural area with a value of 7.5%positivity and 22.5% negativity. Forty (20.0%) of the tested subjects had genotype AA out of which 6 (3.0%) was positive for rhinovirus infection, the remaining 34 (17.0%) were negative for the rhinovirus infection.

Conclusion: This study established the detection of rhinovirus infection in children attending the pediatrics clinic in Ilorin. This may become useful for diagnosing respiratory illness in high-risk populations with immune compromised individuals.

Downloads

Published

2016-04-10

How to Cite

Kolawole, O. M., Adeyemi, B. J., & Gobir, A. A. (2016). Prevalence of Human Rhinovirus Infection in Children with Acute Respiratory Symptoms in Ilorin, Nigeria. The Nigerian Health Journal, 15(2), 62. Retrieved from https://tnhjph.com/index.php/tnhj/article/view/213

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.