Rising Reproductivity in Advanced Age: The Internist’s Involvement

Authors

  • Ekechi Stella Amadi University of Port Harcourt Teaching Hospital, Alakahia Port Harcourt Rivers State.
  • Sukarime Eli University of Port Harcourt Teaching Hospital
  • Erinma Fortuna Pepple University of Port Harcourt Teaching Hospital

Keywords:

Advanced age, Fertility, Internist, Reproduction

Abstract

Background: As the world ages, so is there advancement in knowledge, science and technology which has improved the quality of life of individuals, thus leading to an increase in life expectancy in almost all the regions of the world. Reproduction in elderly females is on the rise due to the acceptability of assisted reproductive technology in treatment of infertility. This is likely to result in an increase of interventions by the internist in this age group during pregnancy.

Methods and Materials: Journals, newspaper and magazine publications of case reports of women who were 60 years and above who gave birth to live babies worldwide were analyzed.  An internet based search of credible websites was also done to verify information and analysis of various factors were done. It is a retrospective cross sectional study of women aged 60 years and above who had live births worldwide.

Aim: To review the involvement of the internist in the management of advanced age pregnancy and its outcome

Results: There were 60 persons aged 60 years and above gathered from the publications, 96.7% of these patients had assisted reproduction. The commonest age range was 60-64 years. Primary infertility without children between the couple was the cause of seeking in vitro fertilization in 50% of cases. 10% of the pregnancies were associated with medical complications such as diabetes and hypertension. 57.7% of the documented birth weights were low birth weight.

Conclusion: The management of pregnancy of advanced maternal age is multidisciplinary of which the internist plays an important role.

Author Biographies

Ekechi Stella Amadi, University of Port Harcourt Teaching Hospital, Alakahia Port Harcourt Rivers State.

Registrar, Internal Medicine UPTH

Sukarime Eli, University of Port Harcourt Teaching Hospital

Consultant, Obstetrics & Gynaecology,

Erinma Fortuna Pepple, University of Port Harcourt Teaching Hospital

Senior Registrar

References

www.// Who.int-sexual and reproductive health// definitions and terminology [cited 2017 Sept 13]

Dag ZO, Dibaz B- Impact of Obesity on Infertility in women J Turk Ger Gynaecol Assoc ; 2015: [Cited 2017 Dec. 25]. Availablefromhttps://www.ncbi. nim.nih.gov/pmc/articles/PMC 4456969

Livshits A, Seidman D.S; Fertility Issues in Women with Diabetes: Women Health, 2009 [Cited 2017 Dec 25] 5(6); 701-707 Available from https://www.medscape.com/viewer/717692_4

Abarikwu SO; Causes and Risk Factors for Male Infertility in Nigeria, A review: African Journal of Reproductive Health 2013 Dec [Cited 2017 Dec.25]. Available from www.bioline.org.br/pdf?rh13065

Monoski M, Nudell DM, Lipshultz LI: Effect of Medical therapy, Alcohol and smoking on Male Infertility; Gontempoary Urology 2002 Jun: 57-63. www.scielo.br/scielo.php?script=sciarttex&pid50041-817812004000

Stillman PJ, Rosenberg MJ,Sachs BP: Smoking and reproduction , Fertil Teril 1986/46(4):545-66

Calogero A, Polosa R, Perdichizzi A , Guarino P. La Vigner S, Scarfin A et al, Cigarrette smoke extract immobilizes human spermatozoa and induces sperm apopotosis: Reprod Biomedline, 2009, 19 564-71

Rosene- Montella K, Keely E, Laifer S.A, Lee R.V; Evaluation and Management of Infertility: The Internist’s role. Annals of Internal Medicine, 2000 Jul [cited 201 Sept 10] 132(12); 973-81; Available from: annals .org/am/article/713549

Longo DL ,Fauci AS , Kasper DL, Hauser SL, Jameson JL, Loscalzo J, editors. Medical disorders in pregnancy. In: Harrison’s Principles of Internal Medicine. 18thed. MaC-Graw Hill coy. 2012, chapter 7

-Herbal medicines for infertility: Facts and safety to boost fertility- American Pregnancy Association. Americanpregnancy.org/infertility/herbs[Cited 2017 Dec 27]

-Ekwere PD- Immunological infertility among Nigerian men, incidence of circulating antisperm autoantibodies and some clinical observations: Apreliminary report. Br J Urol 1995,76:366-7

Adejumo BI, Oke AA, Emokpae MA, Oyeleke AA, Erhabor TA, Agba MI et al . A study of antispermantibodies among infertile subjects investigated for infertility in Lagos, Nigeria Ann Biomed Sci 2014; 31 29-35

Paulson R.J, Booststanfar R, Saa, dat P et al. Pregnancy at the sixth decade of life, Obstetric outcomes in women of advanced reproductive age. JAMA, 2002 [cited 2017 Sept 13] 288(18) 2320-2323. Available from https.jamanetwork.com/journals/jama/article-abstract/195477

Antinori S, Versaci C, Pansi C, Caffa B, Gholami HG. Fetal and maternal morbidity and mortality in menopausal women aged 45-63years Hum Reprod 1995 [Cited 2017 Dec 27] : 10(2) 464-469. Avaialble from citesseerx.ist.psu.edu/viewdoc/download?doi=10.1.898.1850&rep&type=p

- Timofeev J, Reedy UM, Haung C et al. Obstetric complications neonatal morbidity and indications for cesarean delivery by maternal age. Obstet Gynecol 2013,[ cited 2017 Oct 25] 1184-95. Available from https,//www.ncib.nim.nih.gov/pmc/PMC/articles /PMC 4189107

-Reeta L, Katri V.J, Gissler M, Heinonen S. Preeclampsia complicated by advanced maternal age, a registry based study on primiparous women in Finland 1997-2008. BMC Pregnancy and Child birth. 2012 [cited 2017 Oct 25]. Available from https://doi.org/10.1186/1471-2393-12-47

Jim B, Groove VD. Acute Kidney Injury in Pregnancy. Semin Nephrol 2017 Jul [cited 2017 Oct 25] ;37(4):378-385. Available from: http://www.ncbi.nim.nih.gov/pubmed/28711077

Jolly M, Sebire N, Harris J, Robison S, Regan L. The risks associated with pregnancy in women aged 35 years and older. Hum Reprod 2000 Nov [cited 2017 Oct 25] ; 15(11) : 2433-7 Available from; https.www.ncbi.nim.nih.gov/pubmed/11056148

- Hack M, Klein NK, Taylor HG. Long term development of low birth weight infants, Future Child, 1995 [cited 2017 Oct 25] Spring 5(1) 176-196. Available from: https:// www.ncbi nim.nih.gov.gov/pubmed/7543353

-Bjørn EV, Lorentz MI, Torbjørn L, Stein H, Bjørn MI. Low birth weight increases risk for end stage renal disease J Am Soc Nephrol 2008 Jan [cited 2017 Oct 25] 19(1): 151-157 Available from: https;// www.ncbi.nim.nih.gov/pmc/articles/2391041

-Paulson RJ, Thorton MH, Francis MM, Salvador HS, Successful pregnancy in a 63 year old woman, Fertil Steril, 1997 Dec 68 (6) 1153-4

- Boland MR, Shahn Z, Madigan, Hripcsak G, Tatonetti NP. Birth month affects lifetime disease risk: a phenome–wide method J Am Med Inform Assoc 2015; 22:1042-1053.doi;10.1093/jama/ocv046, Research and Applications

- Quesada JA, Nolasco A. Relationship between patient’s month of birth and the prevalence of chronic diseases. Medicina Clinica 2017 Jun[ Cited 2017 Dec 27] 148(11) 489-494 Available from www.sciencedirect.com/science/article/pii/S238702617303388

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Published

2020-08-10

How to Cite

Amadi, E. S., Eli, S., & Pepple, E. F. (2020). Rising Reproductivity in Advanced Age: The Internist’s Involvement. The Nigerian Health Journal, 19(4), 158–166. Retrieved from https://tnhjph.com/index.php/tnhj/article/view/385

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