The Impact of Galactorrhoea on Infertility In Port Harcourt

Isreal Jeremiah, Christian Akani, Vadumeme Kingsley Oriji


Background: Infertility is a major global problem and is regarded as a social stigma in the Nigerian society. At least one in every ten couples of reproductive age has infertility. Galactorrhoea is one of the complaints often associated with infertility. Its relationship with amenorrhoea and infertility is well established. The objective of this study is to determine the incidence and contribution of galactorrhoea to female infertility and to determine any correlation between galactorrhoea and hyperprolactinaemia.

Methods: A descriptive prospective study involving 186 consecutive patients presenting with infertility at the University of Port Harcourt teaching Hospital between 1st January 2009 and 30th June 2009. All patients presenting with infertility at the gynaecological clinic of the University of Port Harcourt Teaching Hospital between 1st January 2009 and 30th June 2009 were included in this study. Data was collected based on a protocol developed for the study. Data collected was entered into a spread sheet using SPSS 14.0 for Windows® statistical software which was also used for analysis.

Results: Galactorrhoea was present in 101 (54%) of the infertile patients. Only 58% of the patients who had galactorrhoea were aware they had galactorrhoea. Galactorrhoea was associated with menstrual abnormalities in 37.8% of the patients, 17% had amenorrhoea while 20.8% had oligomenorrhoea. Hyperprolactinaemia was found in 55% of the study population, 76.9% of these had galactorrhoea while 80% of all patients with galactorrhoea had hyperprolactinaemia. Galactorrhoea (with hyperprolactinaemia) was the only abnormality found in 16.1% of the study population and in 29.7% of those with anovulation.

Conclusion: There is a high incidence of galactorrhoea (54%) and hyperprolactinaemia (55%) amongst infertile women as seen in this study. 16.1% of the study population had galactorrhoea (with hyperprolactinaemia) as the only abnormal finding. Most patients with galactorrhoea would also have Hyperprolactinaemia.There is a positive correlation between galactorrhoea & hyperprolactinaemia, not all women with hyperprolactinaemia had galactorrhoea and vice-versa.


Galactorrhoea; infertility; Nigeria

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ISSN: 1597-4292